Date: May 21, 2024

Time: 11:00 AM - 1:00 PM

Building: Food Safety and Toxicology

Room: 162

The Institute for Integrative Toxicology presents the 3rd Annual Jerry Hook Distinguished Lectureship given by Dr. Jeffrey M. Peters, to speak on, "The Mechanisms of Peroxisome Proliferator-activated Receptor-α (PPARα) Liver Carcinogenesis from Past to Present."

About the Speaker:

Dr. Peters is a Distinguished Professor of Molecular Toxicology and Carcinogenesis, and the Deputy Director of the Penn State Cancer Institute. He has served on many editorial boards including The Journal of Biological Chemistry and he is the Editor-in-Chief for Toxicological Sciences.

Dr. Jeffrey Peters’ laboratory studies the role of the peroxisome proliferator-activated receptors (PPARs). PPARs modulate gene expression through direct and indirect mechanisms. His laboratory group uses genetically modified mouse and human models, high affinity agonists, antagonists and selective, repressive ligands to delineate the roles of PPARs, with a particular interest in cancers. Through their studies, they are elucidating the molecular mechanisms by which exogenous (dietary) and endogenous (metabolic sources) lipids specifically modulate human health.

His team is particularly interested in delineating how natural compounds can modulate PPARs with the goal of identifying new molecules/proteins that can be targeted with existing approaches to improve the efficacy of chemoprevention and chemotherapy.

*Fulfills seminar requirements for the Environmental and Integrative Toxicological Sciences Graduate Programs. Seminars that fulfill this requirement are archived at:

See Institute for Integrative Toxicology events.