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The ARRIVE (Animal Research: Reporting of In Vivo Experiments) guidelines are intended to improve the reporting of research using animals – maximizing information published and minimizing unnecessary studies. The guidelines are produced by the National Centre for the Replacement Refinement & Reduction of Animals in Research (NC3Rs).

The ARRIVE website has a large number of additional resources.

The ARRIVE guidelines, originally published in PLOS Biology, were developed in consultation with the scientific community as part of an NC3Rs initiative to improve the standard of reporting of research using animals. In ARRIVE guidelines were revised in 2020 to create the ARRIVE guidelines 2.0. The ARRIVE guidelines 2.0 split the checklist items into the Essential 10 items and Recommended set.

Checklist

The ARRIVE Guideline 2:0 checklist is here (https://arriveguidelines.org/a...)


The Explanation and Elaboration for the ARRIVE guidelines 2.0 were originally published in PLOS Biology doi:10.1371/journal.pbio.3000411 under a CC-BY license.

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Citation

Updated: The Explanation and Elaboration for the ARRIVE guidelines 2.0 were originally published in PLOS Biologydoi:10.1371/journal.pbio.3000411 under a CC-BY license.

  • Original citations
  • Kilkenny, C., Browne, W. J., Cuthill, I. C., Emerson, M., & Altman, D. G. (2010). Improving bioscience research reporting: the ARRIVE guidelines for reporting animal research.
  • PLoS biology, 8(6), e1000412.
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  • Experimental Physiology 2010 95:842-844 doi:10.1113/expphysiol.2010.053793 PMID:20610776
  • British Journal of Pharmacology 160(7):1577-1579 doi:10.1111/j.1476-5381.2010.00872.x, PMID:20649561
  • Kilkenny C, Browne WJ, Cuthill IC et al. (2014). Improving bioscience research reporting: the ARRIVE guidelines for reporting animal research. Animals 4(1):35-44 doi:10.3390/ani4010035
  • Want an easier way to fill out the ARRIVE checklist?

    1. upload your manuscript
    2. highlight the text that corresponds to the items
    3. download the completed checklist
    4. submit with your manuscript
    Try our new tool!

    The ARRIVE checklist is designed to be used when submitting manuscripts describing animal research. To complete the checklist, fill in the right-hand column with the section and paragraph (e.g. ‘Methods, Paragraph 2’) reporting the ARRIVE item. If the checklist item is not applicable to the study being reported, provide a reason for not reporting this information in the right-hand column. A completed checklist can be provided as supplementary information and will help reviewers and editors to ensure the high-quality reporting of animal research.