Yes. If desired, dilution and repeating the assay can be requested for an additional cost (same price as the original testing), if there is sample remaining at our laboratory.

No. Paraneoplastic hypoglycemia is mediated by IGF-2 which does not cross-react in the IGF-1 assay.

• Yes. The endocrinology laboratory accepts samples from most animals, including non-human primates. However, we do not have reference intervals for these tests. If an interpretation is ordered, you will be provided with comparative statistical data as available from prior samples submitted to the VDL. Results should be interpreted in consideration of the patient history, clinical presentation, current therapeutics, and results of additional diagnostics with recognition that statistics provided include animals whose health status is unknown.
• If an assay manufacturer has indicated an incompatible species, it will be noted in the catalog.
• For bioidentical hormones, some animals may have levels that do not measure within the assay range. Assays for non-bioidentical hormones may not cross-react in certain species. For example, some species consistently measure below the level of detection on the parathyroid hormone assay. The thyroid stimulating hormone assay is a test of uncertain utility in many exotic species. Please call to discuss testing in exotic species if you are uncertain.

The patient must be correctly indicated as neutered or intact on the submittal form for accurate interpretation of testosterone and progesterone results.

• Reference intervals: “Normal” progesterone concentrations in an intact female depend on the stage of the estrus cycle.
• Breeding: Serial progesterone measurement can be used (along with vaginal cytology) to estimate times of ovulation and optimal fertility. A guide for interpretation of progesterone results for breeding purposes can be found on the Assessment of Reproduction page on our website.
• Ovarian remnant: Progesterone may be helpful in detecting ovulation and development of luteal tissue when an ovarian remnant is suspected. Correct interpretation depends upon confidence in the stage of estrus with integration of behavior and physical changes. The VDL does not offer anti-mullerian hormone (AMH) testing.

Ovarian remnant: Measure progesterone 7-14 days after induction of ovulation.

Adrenal tumors: some adrenal tumors secrete multiple hormones including progesterone.

Cryptorchidism: A baseline testosterone measurement can often determine if a dog or cat is cryptorchid or has functional testicular tissue. Occasionally the result is equivocal, and a stimulation test can then be done.

Adrenal tumors (cats): some adrenal tumors in cats secrete multiple hormones including testosterone.