Contact Information

Phone: 517-432-1026


Food Safety and Toxicology Building
1129 Farm Lane, Room Room 211
Michigan State University
East Lansing, MI 48824


  • BS, Biochemistry, Michigan State University, 1984
  • MBA, Logistics Management, Michigan State University, 1992
  • PhD, Pharmacology/Toxicology, Michigan State University, 1998

Research Program

  • To investigate pathophysiological mechanisms of health effects caused by exposure to environmental and occupational air pollutants
  • Conduct translational studies to understand the mechanisms of airway injury and systemic responses induced by inhalation exposures to pathogens, toxicants and environmental pollutants, specifically how they might exacerbate and modify preexisting diseases with unique underlying inflammatory components.
  • Collaborate with atmospheric chemists, occupational hygienists, epidemiologists, nutritionists and health care providers to develop intervention strategies to mitigate the adverse health effects of environmental and occupational air pollutants

Current Investigation

  • Role of diet and metabolic susceptibility in adverse cardiopulmonary responses to air pollutant exposure
  • Mechanisms of airway immune responses to engineered nanomaterials
  • Asthma and allergy associated with agricultural and biogenic dusts

Funding Sources

  • National Institutes of Health/National Institute of Environmental Health Sciences
  • National Institute for Public Health and the Environment -RIVM
  • Private industries

Teaching Interests

  • Toxicology -Inhalation, Occupational, Environmental, Veterinary
  • Pathology – General, Comparative, Inflammation, Immunology
  • Histology – General, Cell Biology, Respiratory, Cardiovascular


  • Member, Committee for Threshold Limit Values for Chemical Substances (TLV-CS); American Conference of Governmental Industrial Hygienists (ACGIH)
  • President, Cardiovascular Specialty Section, Society of Toxicology
  • Member, Finance Committee, Society of Toxicology
  • Associate Editor, Inhalation Toxicology
  • Editorial Board Member, Particle and Fibre Toxicology
  • Peer Review Panels: NIEHS Superfund, NIEHS Children’s Health Centers, NIOSH/CDC World Trade Center, EPA Integrated Science Assessment for PM2.5, Sulfur Oxides