Gastrointestinal researchers at the MSU College of Veterinary Medicine are focused on scientific investigations aimed to benefit both humans and animals. Current research projects include cancer, stress, gut microbiome, and liver toxicology.

Gastrointestinal Researchers

Victor DiRita, PhD

Vibrio cholerae and Campylobacter jejuni

Patricia Ganey, PhD

Mechanisms and consequences of interactions between the inflammatory response and chemicals that lead to toxicity

Jack Harkema, DVM, PhD, DACVP, ATSF

Biological mechanisms underlying airway epithelial cell injury, repair and adaptation; gut microbiota, liver function, and immunity

Sara Jablonski (Wennogle), DVM, PhD, DACVIM (SAIM)

Protein-losing enteropathy, intestinal lymphangiectasia, chronic enteropathies, and hepatobiliary disorders

Daniel Langlois, BS, DVM, DACVIM

Copper-associated diseases and endocrine disorders in dogs and cats

James Luyendyk, PhD

Mechanisms whereby the coagulation cascade contributes to the pathogenesis of liver disease

Dr. James Luyendyk is Professor of Pathobiology and Diagnostic Investigation at Michigan State University (MSU). His research team focuses on mechanisms of hepatotoxicity and liver repair/regeneration, with an emphasis on how components of the blood clotting system participate in acute liver injury and chronic liver disease. He has nearly 120 peer-reviewed publications, has co-edited the Hepatic Toxicology volume of Comprehensive Toxicology and co-authored the liver chapter in Casarett and Doull's Toxicology (8th edition). Dr. Luyendyk is a Fellow of the Academy of Toxicological Sciences and is a recipient of numerous awards from the Society of Toxicology, including the Achievement Award. Dr. Luyendyk has served on numerous NIH Study Sections, including as standing member and Chairperson of XNDA. He holds diverse leadership roles in multiple professional societies, including as Co-chair of the new ISTH SSC on hemostatic management of patients with liver diseases, member of the AASLD hepatotoxicity special interest group steering committee, and as secretary and Council member of the Society of Toxicology.

Linda Mansfield, MS, VMD, PhD, DACVM

Enteric pathogens resulting in GI tract inflammation; Campylobacter jejuni; therapies for IBD

Adam Moeser, MS, PhD, DVM

Interactions between early-life stress, biological sex in shaping gut neuroimmune development, disease risk

Robert Roth, PhD

Inflammation as a determinant of sensitivity to toxic agents

Victoria Watson, DVM, PhD, DACVP

Interactive roles of pathogenic organisms, members of the gut microbiome, and barrier function of the intestinal tract in health and disease

Vilma Yuzbasiyan-Gurkan, PhD

Comparative molecular genetics, cancer genetics, canine genome mapping