The Johnston Laboratory seeks to understand sexual dimorphism in metabolic dysfunction-associated steatotic liver disease (MASLD) & lipid metabolism in hepatocellular carcinoma (HCC). Additionally, the lab focuses on developing diagnostic and therapeutic methods that will improve survival outcomes and quality of life in dogs and cats with hepatobiliary disease.
CURRENT INVESTIGATIONS
- Lipid metabolism and mitochondrial dysfunction in HCC
- Sexual dimorphism in MASLD & HCC
- Hepatobiliary neuroendocrine neoplasms
- Fibropolycystic liver disease (dogs, cats)
FUNDING SOURCES
- NIH, NIGMS
- Comparative Gastroenterology Society
TEACHING INTERESTS
- Hepatobiliary disease
PROFESSIONAL MEMBERSHIPS
- American Association for The Study of Liver Diseases, AASLD
- American College of Veterinary Internal Medicine, ACVIM
- Comparative Gastroenterology Society, CGS
- Comparative Hepatology Society, CHS