The Laboratory for Environmental and Toxicologic Pathology investigates a wide range of variable affecting pulmonary health including environmental factors, individual biology, and translational medicine.

Jack Harkema, DVM, PhD, DACVP, ATSF, is investigating biological mechanisms underlying airway epithelial cell injury, repair and adaptation to air pollutants, allergens, and microbial toxins; how pre-existing disease may affect an individual's susceptibility to air pollutants, such as particulate matter and ozone; the use of mobile air research laboratories to study the inhalation effects of air pollution; and the role of the lymphoid cells in the allergic response and modulation of immune response with diet. Harkema is the Albert C. and Lois E. Dehn Endowed Chair in Veterinary Medicine for the Department of Pathobiology and Diagnostic Investigation.

James Wagner, MBA, PhD, is investigating mechanisms of airway injury and systemic responses induced by inhalation exposures to pathogens, toxicants, and environmental pollutants; how pathogens, toxicants, and environmental pollutants might exacerbate and modify pre-existing diseases with unique underlying inflammatory components; and cardiopulmonary responses to particulate matter and ozone inhalation including the effects of lung and cardiovascular functions.