Respiratory health researchers at the Michigan State University College of Veterinary Medicine are dedicated to understanding the mechanisms that underlie respiratory diseases in order to identify preventative medicine strategies, develop novel therapies and interventions, and promote environmental and public health awareness, with the ultimate goal of optimizing airway health and avoiding or eliminating diseases of the upper and lower respiratory tract. Embracing the principles of a One Health approach, researcher interests range from the effects of airborne pollutants, modulation of disease by genetic and epigenetic risk factors, elucidation of disease etiology and biological mechanisms, the roles of the microbiome, and other integrative lines of investigation that will produce new knowledge that can be used to improve respiratory health of animals and humans.