Azam Ali Sher

Degree Seeking

PhD; Dual Doctoral Program: CMIB and EITS (Biomedical Toxicology)

Prior Degrees

  • DVM; University of Agriculture Faisalabad
  • MS; Epidemiology, Michigan State University

Mentor(s)

Linda Mansfield

Research Interests

The emergence and global spread of antimicrobial resistance (AMR) among bacterial pathogens against life-saving drugs have become a major challenge for public health and clinical settings. My PhD research focuses on understanding the gut microbiome's mechanistic role in the emergence and transmission of AMR in commensals and pathogenic bacteria and exploring different dynamics of the gut microbiota pre and post-antibiotic treatment. I am currently working on building an in-vivo animal-based system that mimics the human gut to address this complex scientific question by integrating different Omics and synthetic biology techniques. This study will lead us to uncover different drug-microbiome-host interactions and find some solutions to halt AMR in the gut and environment.

CMIB Publications

Sher, Azam A., John P. Jerome, Julia A. Bell, Julian Yu, Hahyung Y. Kim, Jeffrey E. Barrick, and Linda S. Mansfield. 2020. “Experimental Evolution of Campylobacter Jejuni Leads to Loss of Motility, RpoN (σ54) Deletion and Genome Reduction.” Frontiers in Microbiology 11 (November): 2781. https://doi.org/10.3389/fmicb.2020.579989.

Sher, Azam Ali, Muhammad Adnan Ashraf, Bahar-E Mustafa, and Muhammad Mohsin Raza. 2021. “Epidemiological Trends of Foodborne Campylobacter Outbreaks in the United States of America, 1998–2016.” Food Microbiology, January, 103751. https://doi.org/10.1016/j.fm.2021.103751.

Sher, A.A, Bahar-E-Mustafa, Sue C. Grady, and Joseph C. Gardiner, A. Mahdi Saeed. 2021. “Outbreaks of Foodborne Salmonella Enteritidis in The United States 1990-2015: Epidemiologic and Spatial-temporal Trends Analyses.” Intl. Journal of Infectious Diseases, (Accepted, Feb 2021).