Contact Information

Email: lining3@msu.edu

Phone: 517-884-2075

Education

• MD, Capital Medical University, Beijing, China
• MS, University of Wisconsin-Madison, WI, Madison
• PhD, University of Wisconsin-Madison, WI, Madison
• Post-graduate fellow, Universitair Ziekenhuis Antwerpen, Antwerp, Belgium
• Postdoctoral Researcher, University of California Los Angeles, Los Angeles, CA

Research Program

• To identify the association between the chemical activities of ambient air pollutants and the malignant behavior of human lung cancer and related biomarkers
• Understanding how multi-pollutant interactions (e.g., particulate matter, vapor and ozone) contribute to asthma pathogenesis and exacerbation
• Investigating the mechanisms by which air pollutants of different sources (e.g., vehicular emissions, commercial cooking and biomass combustion) promote asthma

Current Investigation

• The impact of changes in amount and composition of ambient air pollutants on the induction and progression of human lung cancer and underlying mechanisms
• The additive/synergistic adjuvant effects of multi-pollutant interactions on allergic sensitization
• Interference with antigen presenting dendritic cell function as a major mechanism for the pro-allergic and pro-inflammatory effects of commercial charbroiling meat emissions
• The role of oxidative stress in cellular injuries induced by sugarcane-burning smoke in normal and asthmatic human airway epithelial cells

Funding Sources

• South Coast Air Quality Management District, CA
• MSU internal funding: OVPRGS, CVM, COM

Education

• Immunology focusing on antigen presenting dendritic cells
• Inflammation and allergic inflammation
• Toxicological mechanisms involving oxidative stress and antioxidant defense
• Inhalation toxicology
• Immunotoxicology